An introduction to eukaryotic and prokaryotic cell structure and function, and the chemistry of life. The flow of information within cells and transmission of genetic information to progeny in cell division. A description of cellular mechanisms for creating genetic diversity and the control of gene expression. An introduction to molecular genetics and genomics.
An introductory course in biology suitable for students with little previous experience in the subject. Topics include: the diversity of life; cells as the basic unit of life; form and function of cells, microbes, animals and plants; DNA and molecular genetics; classical genetics; evolution and ecology.
162.211 Biology and Genetics of Microorganisms15 credits
Structure and metabolism of bacteria and their relation to the environment. Bacterial genetics. Eukaryote microbes - structure, physiology and genetics. Life cycle of viruses. The immune response. Practical training in the manipulation of micro-organisms.
Microbiology as an integrated study of the diversity of micro-organisms and microbial environments. The range of microbial cell structures and metabolism is described in relation to environmental niches, and the molecular mechanisms for responding to environmental change. Actions and interactions of micro-organisms in soil and water.
Structure and metabolism of bacteria with particular reference to food and environmental microbiology. Bacterial genetics. Eukaryote microbes - structure, physiology and genetics. Life cycle of viruses. The immune response. Practical training in the manipulation of micro-organisms.
An introduction to the general principles of host-pathogen interaction for some major groups of bacteria and fungi pathogenic for humans. Detection of pathogens in clinical specimens. Sterilisation, disinfection and control of microbial growth. Antimicrobial agents, resistance to antimicrobial agents and antimicrobial susceptibility testing.
Some major bacterial pathogens of humans in terms of the organisms, their habitats, modes of transmission, disease patterns and laboratory diagnosis. The structure, classification, propagation, assay and transmission of some of the major viruses of humans. Immunity to viruses and the laboratory diagnosis of viral infections.
The principles of immunology including innate immunity, cell and antibody mediated immunity, the major histocompatibility complex, the hypersensitivities, immunodeficiency and autoimmunity. An introduction to vaccines, clinical immunology and immunological laboratory tests.
162.304 Applied and Environmental Microbiology15 credits
Actions and interactions of micro-organisms in soil, water, air, food, and the animal and human gut; consequences and applications of microbial colonisation processes.
Current topics in microbiology covering topics in pathogenicity, biofilms, host interactions and industrial applications.
162.760 Research Methods and Communication in the Biosciences30 credits
A directed course in research methodology and communication in biosciences. Assignments may include a research proposal, a literature review, scientific writing for a journal and a formal seminar presentation.